M19 Density/Porosity Analyzer (Helium Pycnometer) for pharmaceutical — AI-based, ultra-high-precision testing. Standards: USP 699, ASTM B923-10.
Model: Helium Pycnometer · Industry: Pharma
The M19 Density/Porosity Analyzer (helium pycnometer) measures the true (skeletal) density of pharmaceutical powders, tablets and granules by gas displacement, applying Boyle’s law under isothermal conditions. Because helium accesses even the finest open pores, the instrument resolves true density independent of particle shape or bulk packing. True density underpins purity assessment, tablet-compression studies, powder characterization and granule evaluation. Aligned with USP <699> (Density of Solids), the analyzer gives formulators and QC teams a reliable measure of composition and consistency across development and manufacturing.
| Specification | Value |
|---|---|
| Test Range | 10 – 135 cc |
| Modes | True / skeletal density |
| Use case | Adsorbents & porosity workflows |
| Repeatability | High precision |
| Output | Structured datasets |
It provides gas-displacement density and porosity data: True (skeletal) density via helium pycnometry Open porosity and pore volume when paired with envelope density Batch-to-batch density consistency Purity and composition indicators
Helium accesses fine open pores without wetting, dissolving or contaminating the sample, giving faster, more accurate true-density values than mercury or liquid methods — with no hazardous reagents.
The isothermal Boyle’s-law approach: Measures true sample volume precisely Compensates for temperature and pressure drift Uses automated multi-cycle averaging Self-calibrates for zero-drift performance
Local build delivers: Faster service and local support Reduced lead time and spare-parts availability Lower import cost and easy customisation 2-year warranty with on-site support
Yes — secure electronic records, audit trails and PDF/CSV export let density results feed directly into specifications, compression studies and batch documentation.
Method alignment to USP <699> and ASTM B923, plus 21 CFR Part 11 records and IQ/OQ/PQ documentation, keeps density data audit-ready for US FDA, EU GMP and WHO GMP.