What does the Helium Pycnometer measure for biotech applications?
It characterizes true (skeletal) density and open porosity by helium displacement, giving biotech teams quantitative data for media design, supplier qualification and lot acceptance.
EXPERIENCE THE Most Advanced Density/Porosity Analyzer
M19 Density/Porosity Analyzer (Helium Pycnometer) for biotech — AI-based, ultra-high-precision testing. Standards: USP 699, ASTM B923-10.
Model: Helium Pycnometer · Industry: Biotech
Technology principle
The M19 Density/Porosity Analyzer (Helium Pycnometer) measures true (skeletal) density and open porosity by helium displacement for materials used across bioprocess, single-use and biotech R&D. Configured for sterile filtration, membrane performance and audit-ready bioprocess documentation, it delivers repeatable, audit-ready data so biotech teams can qualify media, accelerate development and defend specification decisions. Referenced to USP 699, ASTM B923-10, the platform combines precise hardware control with electronic records suitable for regulated and industrial quality systems.
Applications
- Resin bead density
- Lyophilised cake porosity
- Excipient powders
- Carrier solids
Key capabilities
- Lightweight, compact and ergonomically engineered, the M19 Density/Porosity Analyzer (Helium Pycnometer) pairs a 15" capacitive touchscreen with enhanced pressure- and flow-control hardware, so operators run a full biotech test sequence with minimal training and shorter cycle times. Available in aluminum or stainless-steel variants, it ships with real-time remote support, USB connectivity and remote-control automation. Domestic manufacturing in India and the USA keeps maintenance cost and downtime low, and a 2-year extended warranty is available.
- Modern, low-training user interface
- Lightweight and portable chassis
- IP65 rated · GAMP 5 compliant
- Three secure user levels — Operator, Supervisor and Administrator
- Versatile connectivity — USB, Ethernet and Wireless LAN
- Flexible reporting — built-in thermal printer or network / PDF / CSV export
Technical specifications
| Specification | Value |
|---|---|
| Test Range | 10 – 135 cc |
| Modes | True / skeletal density |
| Use case | Adsorbents & porosity workflows |
| Repeatability | High precision |
| Output | Structured datasets |
Standards compliance
- USP 699
- ASTM B923-10
Frequently asked questions
Which standards apply in biotech workflows?
Typical references include USP 699, ASTM B923-10. Method templates can be aligned to your internal SOP and customer specifications.
How does the software support audits and quality systems?
Electronic signatures, tamper-proof audit trails, role-based access and PDF/CSV export support regulated and industrial quality workflows, including LIMS hand-off.
Can the instrument be customised for our materials?
Yes — sample holders, pressure/flow ranges and report templates can be configured for biotech-specific media and acceptance criteria.
What are the advantages of indigenous manufacturing?
Make-in-India / USA build delivers faster service, spare-parts availability, lower cost of ownership and easier customisation — with extended warranty options.
How do we get started?
Book a demo with your sample set, download the brochure, or request a quote for an industry-configured system with IQ/OQ documentation support.